Research Interests

Our research aims to address two overarching questions:

 

How do synapses and cells within the brain adapt to encode learning?

 

How do the cellular process that support learning go awry in neurodevelopmental disorders

Our experimental approach

Electrophysiology

Patch-clamp recordings from cerebellar neurons, with a particular focus on the properties and plasticity of Purkinje cells

Molecular methods and genetic tools

These allow us to visualize, modify, and analyze cellular and sub-cellular properties

Behavior

Induction and analysis of learned, cerebellum-dependent behaviors